GLEMITOL M2 combines Metformin and Glimepiride to provide effective blood sugar management in adults with type 2 diabetes mellitus. Metformin, a biguanide, reduces glucose production in the liver and enhances insulin sensitivity, while Glimepiride, a sulfonylurea, stimulates the pancreas to release more insulin. This dual-action formulation helps maintain stable blood glucose levels throughout the day and reduces the risk of diabetes-related complications. GLEMITOL M2 is available in 10x10 blister packaging.
HOW DOES IT WORK?
Metformin works by decreasing hepatic glucose production and increasing peripheral insulin sensitivity, which helps reduce fasting blood glucose levels.
Glimepiride increases insulin release from pancreatic beta cells, particularly effective in lowering postprandial (after-meal) blood glucose levels.
This combination addresses both fasting and post-meal glucose levels, making it a comprehensive solution for type 2 diabetes management.SIDE EFFECTSWhile GLEMITOL M2 is generally well-tolerated, some patients may experience side effects, such as:
Hypoglycemia (especially with improper dosing or skipping meals)
Nausea
Diarrhea
Mild weight gain
Dizziness
Consult a healthcare provider if side effects persist or worsen. Metformin may rarely cause lactic acidosis, a serious side effect requiring immediate medical attention.ADMINISTRATION OF DOSESGLEMITOL M2 is typically prescribed as one tablet taken once or twice daily with meals to reduce the risk of gastrointestinal discomfort and hypoglycemia. Patients should strictly follow their healthcare provider’s dosage instructions, avoiding any alterations in the prescribed dose.
BENEFITS
Provides effective control of blood sugar levels, targeting both fasting and postprandial glucose levels(Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 13th Edition)
Helps reduce the risk of diabetes complications by maintaining stable blood glucose levels(Katzung & Trevor's Basic and Clinical Pharmacology, 14th Edition)
INDICATIONSGLEMITOL M2 is indicated for:
Management of type 2 diabetes mellitus in adults when diet and exercise alone are insufficient to control blood glucose(Harrison's Principles of Internal Medicine, 20th Edition)
PRECAUTIONSUse GLEMITOL M2 cautiously in patients with kidney or liver impairment, heart failure, or a history of hypoglycemia. Excessive alcohol intake should be avoided, as it can increase the risk of lactic acidosis with Metformin and hypoglycemia with Glimepiride. This medication is not suitable for patients with type 1 diabetes or diabetic ketoacidosis. Pregnant or breastfeeding women should consult their healthcare provider before using this medication. Regular monitoring of blood glucose levels and kidney function is recommended.PLEASE NOTEAlways consult your doctor before taking GLEMITOL M2 or any diabetes medication. Only a healthcare provider can determine if this medication is suitable for you based on your medical history and individual health needs. This information is for educational purposes and should not replace professional medical advice. Avoid self-prescribing diabetes medications without consulting a healthcare provider.