LETOGIV 2.5 contains Letrozole, a non-steroidal aromatase inhibitor, used primarily in the treatment of hormone receptor-positive breast cancer in postmenopausal women. By lowering estrogen levels, Letrozole helps reduce the growth of hormone-sensitive tumours. It’s also used in other hormonal conditions as directed by a healthcare provider. LETOGIV 2.5 is available in 10x1x5 blister packaging.
HOW DOES IT WORK?
Letrozole works by inhibiting the aromatase enzyme, responsible for converting androgens into estrogen in postmenopausal women. Since some breast cancers rely on estrogen to grow, lowering estrogen levels with Letrozole effectively slows or stops tumour progression. This makes LETOGIV 2.5 a valuable part of hormonal therapy for breast cancer management.
SIDE EFFECTS
While LETOGIV 2.5 is generally effective, some patients may experience side effects, including:
Hot flashes
Fatigue
Nausea
Joint or muscle pain
Headache
Dizziness
Consult a healthcare provider if any side effects persist or worsen. Letrozole may also lead to bone thinning or osteoporosis with long-term use, so bone density monitoring may be recommended.
ADMINISTRATION OF DOSES
LETOGIV 2.5 is usually prescribed as one tablet taken once daily, with or without food. It’s important to take it at the same time each day to maintain consistent hormone suppression. Dosage adjustments are generally unnecessary, but patients should follow their healthcare provider's instructions closely.
BENEFITS
Reduces estrogen production to inhibit the growth of estrogen-dependent tumors(Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 13th Edition)
Effective as a long-term management option for hormone receptor-positive breast cancer(Harrison's Principles of Internal Medicine, 20th Edition)
INDICATIONS
LETOGIV 2.5 is indicated for:
Treatment of hormone receptor-positive breast cancer in postmenopausal women(Katzung & Trevor's Basic and Clinical Pharmacology, 14th Edition)
PRECAUTIONS
LETOGIV 2.5 should be used cautiously in patients with a history of liver or kidney disease, osteoporosis, or high cholesterol. Bone density monitoring is advised for long-term users due to the risk of bone thinning. This medication is not suitable for premenopausal women, pregnant women, or breastfeeding mothers due to potential risks to the fetus or infant. Avoid alcohol consumption, as it may exacerbate side effects.PLEASE NOTEAlways consult your doctor before taking LETOGIV 2.5 or any hormone therapy medication. Only a healthcare provider can determine if this medication is appropriate for you based on your medical history and current health condition. The information provided here is for educational purposes and should not replace professional medical advice. Do not self-prescribe this medication or take it without a doctor’s supervision.