ETORILUM contains Etoricoxib, a selective COX-2 inhibitor, commonly known as a nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. Etoricoxib is typically prescribed for pain management in conditions such as osteoarthritis, rheumatoid arthritis, and other chronic musculoskeletal disorders. Its selectivity for COX-2 inhibition minimizes gastrointestinal side effects, making it a preferred choice for long-term pain management in certain patients.HOW DOES IT WORK?Etoricoxib selectively inhibits the COX-2 enzyme, responsible for producing prostaglandins that cause pain and inflammation. By blocking COX-2, Etoricoxib effectively reduces inflammation and pain without substantially affecting the COX-1 enzyme, which protects the stomach lining. This makes ETORILUM beneficial for those requiring long-term relief from pain associated with inflammatory conditions. However, due to its selectivity, it does not completely eliminate gastrointestinal risks and should be used with caution.SIDE EFFECTSWhile ETORILUM is generally well tolerated, some patients may experience mild side effects. Common side effects include:
Dizziness
Headache
Hypertension (high blood pressure)
Indigestion
Nausea
Gastric discomfort
Swelling or edema in certain body parts
Patients should consult a doctor if side effects persist or worsen. In rare cases, Etoricoxib may increase the risk of cardiovascular issues, particularly in patients with pre-existing heart disease.ADMINISTRATION OF DOSESETORILUM is typically prescribed as a once-daily oral tablet, which can be taken with or without food. For osteoarthritis, rheumatoid arthritis, and other chronic pain conditions, the recommended dose is 90 mg daily, as prescribed by a healthcare provider. Patients with liver or kidney impairment may require dose adjustments. Regular monitoring of blood pressure is recommended while on Etoricoxib therapy.BENEFITS
Effective for chronic pain relief in osteoarthritis and rheumatoid arthritis(Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 13th Edition)
Minimizes inflammation and pain without significant GI discomfort(Rang & Dale's Pharmacology, 9th Edition)
Suitable for conditions requiring long-term NSAID use(Martindale: The Complete Drug Reference, 39th Edition)
INDICATIONSETORILUM is indicated for the relief of pain and inflammation in:
Osteoarthritis(Harrison's Principles of Internal Medicine, 20th Edition)
Rheumatoid arthritis(Katzung & Trevor's Basic and Clinical Pharmacology, 14th Edition)
Ankylosing spondylitis(Davidson's Principles and Practice of Medicine, 23rd Edition)
Acute gouty arthritis(Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 13th Edition)
Chronic low back pain or musculoskeletal pain(Martindale: The Complete Drug Reference, 39th Edition)
PRECAUTIONSPatients with known cardiovascular disease, hypertension, or kidney dysfunction should use ETORILUM with caution. Etoricoxib is not recommended for use in patients with severe heart failure, active peptic ulceration, or inflammatory bowel disease. Regular monitoring of blood pressure is essential. Avoid concurrent use with other NSAIDs unless recommended by a healthcare professional. Pregnant and breastfeeding women should avoid this medication unless prescribed, as it may have adverse effects on fetal development.