Sitagliptin phosphate 50 mg + Metformin Hydrochloride 500 mg

SITAPRED-M 50/500

₹3,100.00

Sitagliptin phosphate 50 mg + Metformin Hydrochloride 500 mg

Description Benefits Administration of Dosage Side Effects Precautions and & Disclaimer

SITAPRED 50/500 is a combination medication containing Sitagliptin and Metformin, used to manage blood sugar levels in adults with type 2 diabetes mellitus. Sitagliptin is a DPP-4 inhibitor that enhances the body’s natural incretin hormones to increase insulin release and lower glucagon levels. Metformin, a first-line antihyperglycemic, helps decrease hepatic glucose production and improves insulin sensitivity. Together, this combination provides effective glycemic control and reduces the risk of diabetes-related complications. SITAPRED 50/500 is available in 10x15 blister packaging. HOW DOES IT WORK? Sitagliptin inhibits the enzyme DPP-4, which degrades incretin hormones. By preserving incretin activity, Sitagliptin helps the body produce more insulin when needed and reduces excess sugar production by the liver. Metformin primarily reduces glucose production in the liver and improves the body’s response to insulin, helping lower blood sugar levels. This dual action effectively controls blood glucose levels without significantly increasing the risk of hypoglycemia. SIDE EFFECTS While SITAPRED 50/500 is generally well-tolerated, some side effects may include:

Nausea
Diarrhea
Headache
Upper respiratory tract infection
Hypoglycemia (in rare cases)

Patients should consult a healthcare provider if any side effects persist or worsen. Metformin may rarely cause lactic acidosis, a serious side effect that requires immediate medical attention. ADMINISTRATION OF DOSES SITAPRED 50/500 is typically prescribed as one tablet taken once or twice daily with meals to minimize gastrointestinal side effects. Dosage adjustments may be required based on individual glycemic control and tolerance. It is essential for patients to follow their healthcare provider’s dosing instructions closely and not exceed the recommended dosage. BENEFITS

Helps control blood sugar levels in adults with type 2 diabetes, reducing the risk of long-term complications (Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 13th Edition)
Offers complementary mechanisms of action, improving insulin release and sensitivity while reducing hepatic glucose production (Katzung & Trevor's Basic and Clinical Pharmacology, 14th Edition)

INDICATIONS SITAPRED 50/500 is indicated for:

Management of blood sugar levels in adults with type 2 diabetes when diet and exercise alone are insufficient (Harrison's Principles of Internal Medicine, 20th Edition)

PRECAUTIONS Patients with a history of kidney or liver disease, heart failure, or lactic acidosis should use SITAPRED 50/500 with caution. Avoid excessive alcohol consumption, as it can increase the risk of lactic acidosis with Metformin. Pregnant or breastfeeding women should consult a healthcare provider before using this medication. Regular monitoring of blood glucose levels and kidney function is recommended. This medication is not intended for use in type 1 diabetes or diabetic ketoacidosis. PLEASE NOTE Always consult your doctor before taking SITAPRED 50/500 or any diabetes medication. Only a healthcare provider can determine if this medication is appropriate based on your medical history and individual health needs. The information provided here is for educational purposes and should not replace professional medical advice. Avoid self-prescribing diabetes medications without consulting a healthcare provider.

SITAPRED-M 50/500

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