GLEMITOL MV 2/0.2 is a combination tablet containing Metformin, Glimepiride, and Voglibose, specifically designed for adults with type 2 diabetes mellitus to manage blood sugar levels effectively. Metformin reduces glucose production in the liver and improves insulin sensitivity, Glimepiride stimulates pancreatic insulin release, and Voglibose, an alpha-glucosidase inhibitor, slows down carbohydrate absorption in the intestines. Together, this combination addresses blood glucose spikes after meals and provides comprehensive glycemic control throughout the day. GLEMITOL MV 2/0.2 is available in 10x10 blister packaging.
HOW DOES IT WORK?
Metformin reduces hepatic glucose production and improves insulin sensitivity, primarily lowering fasting blood glucose levels.
Voglibose inhibits intestinal enzymes that convert complex carbohydrates into glucose, slowing down carbohydrate absorption and helping to control post-meal blood glucose spikes.
This combination is highly effective in managing both fasting and postprandial glucose levels, which is crucial for achieving optimal blood sugar control in type 2 diabetes.
SIDE EFFECTS
While GLEMITOL MV 2/0.2 is generally well-tolerated, some patients may experience side effects, including:
Hypoglycemia, especially with improper dosing or skipping meals
Nausea
Diarrhea
Abdominal bloating
Mild weight gain
Flatulence
Consult a healthcare provider if any side effects persist or worsen. Rarely, Metformin may cause lactic acidosis, a serious condition requiring immediate medical attention.
ADMINISTRATION OF DOSES
GLEMITOL MV 2/0.2 is typically taken as one tablet with meals to minimize gastrointestinal discomfort and manage postprandial glucose levels. Dosing should be strictly followed according to the healthcare provider’s instructions, and patients should avoid adjusting doses without medical guidance.
BENEFITS
Provides comprehensive glycemic control by addressing both fasting and postprandial blood sugar levels(Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 13th Edition)
Reduces the risk of diabetes-related complications through effective blood glucose management(Katzung & Trevor's Basic and Clinical Pharmacology, 14th Edition)
INDICATIONS
GLEMITOL MV 2/0.2 is indicated for:
Management of blood sugar levels in adults with type 2 diabetes mellitus when diet and exercise alone are insufficient(Harrison's Principles of Internal Medicine, 20th Edition)
PRECAUTIONS
Use GLEMITOL MV 2/0.2 cautiously in patients with kidney or liver impairment, heart failure, or a history of hypoglycemia. Excessive alcohol intake should be avoided, as it may increase the risk of lactic acidosis with Metformin and hypoglycemia with Glimepiride. Voglibose may cause gastrointestinal side effects, so patients should be informed about the possibility of bloating or gas. This medication is not suitable for individuals with type 1 diabetes or diabetic ketoacidosis. Pregnant or breastfeeding women should consult a healthcare provider before using this medication. Regular monitoring of blood glucose, kidney function, and liver function is recommended.PLEASE NOTEAlways consult your doctor before taking GLEMITOL MV 2/0.2 or any diabetes medication. Only a healthcare provider can determine if this medication is appropriate based on your medical history and individual health needs. The information provided here is for educational purposes and should not replace professional medical advice. Avoid self-prescribing diabetes medications without consulting a healthcare provider.